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Levocetirizine, sold under the brand name Xyzal, among others, is a second-generation antihistamine used for the treatment of allergic rhinitis (hay fever) and long-term hives of unclear cause. [3] It is less sedating than older antihistamines. [ 4 ]
The unbound or free fraction of levocetirizine has been reported to be 8%. [7] The true volume of distribution of cetirizine is unknown but is estimated to be 0.3 to 0.45 L/kg. [9] [7] Cetirizine poorly and slowly crosses the blood–brain barrier, which is thought to be due to its chemical properties and its activity as a P-glycoprotein substrate.
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.
Children with milder forms of peanut sensitivity may be able to overcome their allergy by consuming increasing amounts of store-bought peanut butter, a new study suggests. All of the 32 children ...
Samantha Bee is clapping back at “Saturday Night Live” boss Lorne Michaels, who makes a diss at her in his upcoming memoir “Lorne: The Man Who Invented Saturday Night Live.” The former ...