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  2. Eplerenone - Wikipedia

    en.wikipedia.org/wiki/Eplerenone

    Eplerenone differs from spironolactone in its extensive metabolism, with a short half-life and inactive metabolites. [4] Eplerenone seems to be about 50 to 75% as potent as spironolactone as an antimineralocorticoid. [24] Hence, 25 mg/day spironolactone may be equivalent to approximately 50 mg/day eplerenone. [25]

  3. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Spironolactone has shorter half-life (t1/2 = 1.3-1.4 hours) than eplerenone (t1/2 = 4–6 hours). Eplerenone goes through rapid metabolism by the liver to inactive metabolites (t1/2 = 4–6 hours). However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a ...

  4. Half-Life 2 - Wikipedia

    en.wikipedia.org/wiki/Half-Life_2

    Half-Life 2 was selected by readers of The Guardian as the best game of the decade, with particular praise for the environment design. The Guardian journalist Keith Stuart wrote that it "pushed the envelope for the genre, and set a new high watermark for FPS narrative". [72] Half-Life 2 won Crispy Gamer's Game of the Decade [73] tournament ...

  5. C24H30O6 - Wikipedia

    en.wikipedia.org/wiki/C24H30O6

    Eplerenone, a steroidal antimineralocorticoid of the spirolactone group; Estriol triacetate, an estrogen medication and an estrogen ester

  6. Half-Life 2: Episode One - Wikipedia

    en.wikipedia.org/wiki/Half-Life_2:_Episode_One

    Half-Life 2: Episode One is a 2006 first-person shooter game developed and published by Valve for Windows. It continues the story of Half-Life 2 (2004). As the scientist Gordon Freeman, players must escape City 17 with Gordon's companion Alyx Vance. Like previous Half-Life games, Episode One combines shooting, puzzles and storytelling.

  7. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/projects/dying-to-be...

    Federal stats presented at a June forum showed that out of 625,000 eligible physicians nationwide, only 25,000 are certified to prescribe buprenorphine. A mere 2.5 percent of all primary care doctors have gone through the certification process. “I cannot say it enough,” said then-Sen. Carl Levin (D-Mich.) at the meeting.

  8. Half-Life (series) - Wikipedia

    en.wikipedia.org/wiki/Half-Life_(series)

    In December 2008, Valve announced that the two main Half-Life games had sold 15.8 million units in retail (9.3m for the first, 6.5m for the second), while the Half-Life expansions [85] had sold 1.9 million (Opposing Force: 1.1 million, Blue Shift: 800,000) and Half-Life 2 expansions 1.4 million units (all for Episode One) by the end of November ...

  9. Half-Life 2: Episode Two - Wikipedia

    en.wikipedia.org/wiki/Half-Life_2:_Episode_Two

    Half-Life 2: Episode Two is a 2007 first-person shooter game developed and published by Valve. Following Episode One (2006), it is the second of two shorter episodic games that continue the story of Half-Life 2 (2004).