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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. [8] [9] In CLL, the bone marrow makes too many lymphocytes, which are a type of white blood cell. [8] [9] Many people do not have any symptoms when they are first diagnosed. [8] [2] Those with symptoms may experience fevers, fatigue, night sweats, and ...

  3. Venetoclax - Wikipedia

    en.wikipedia.org/wiki/Venetoclax

    In the EU, venetoclax monotherapy is indicated for the treatment of chronic lymphocytic leukemia (CLL) in the presence of 17p deletion or TP53 mutation in adults who are unsuitable for or have failed a B cell receptor pathway inhibitor and for the treatment of CLL in the absence of 17p deletion or TP53 mutation in adults who have failed both ...

  4. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    Hematologists base CLL treatment on both the stage and symptoms of the individual person. A large group of people with CLL have low-grade disease, which does not benefit from treatment. Individuals with CLL-related complications or more advanced disease often benefit from treatment. In general, the indications for treatment are:

  5. Chronic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_leukemia

    Chronic lymphocytic leukemia, including Hairy cell leukemia; Myeloproliferative neoplasms including polycythemia vera, essential thrombocythemia, primary myelofibrosis, chronic neutrophilic leukemia , and chronic eosinophilic leukemia

  6. Ofatumumab - Wikipedia

    en.wikipedia.org/wiki/Ofatumumab

    Ofatumumab (Arzerra 100 mg or 1000 mg concentrate for solution for infusion) is indicated for the treatment of untreated, relapsed, or refractory chronic lymphocytic leukemia (CLL). [ 8 ] [ 20 ] [ 6 ] [ 21 ] The recommended doses for treatment of CLL are higher than MS, with 1000 or 2000 mg infusions administered monthly depending on if the CLL ...

  7. Phosphoinositide 3-kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Phosphoinositide_3-kinase...

    Idelalisib (trade name Zydelig; codenamed CAL-101, GS-1101; PIK3CD inhibitor): FDA-approved in July 2014 for treatment of three types of blood cancers: treatment of relapsed or refractory chronic lymphocytic leukemia (CLL) in combination with rituximab, treatment of relapsed small lymphocytic lymphoma after at least two prior systemic therapies, and treatment of follicular lymphoma (FL) after ...

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