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Carbapenems are the treatment of choice for serious infections due to ESBL-producing organisms, yet carbapenem-resistant (primarily ertapenem-resistant) isolates have recently been reported. [16] ESBL-producing organisms may appear susceptible to some extended-spectrum cephalosporins. However, treatment with such antibiotics has been associated ...
Overuse of antimicrobial agents and problems with infection control practices have led to the development of multidrug-resistant gram-negative bacterial infections. We used to use carbapenems as the main option in several countries for those severe infections; however, now there are several mechanisms of resistance, including carbapenemase ...
Infections are generally sensitive to antibiotics designed for this bacteria class, though complicated by inducible resistance mechanisms, [5] particularly lactamase; infections accordingly become quickly resistant to standard antibiotics during treatment, necessitating a change in antibiotic to avoid worsening of the sepsis.
NDM-1 [1] is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics.These include the antibiotics of the carbapenem family, which are a mainstay for the treatment of antibiotic-resistant bacterial infections.
Extended-spectrum beta-lactamase–producing E. coli (ESBL E. coli) are highly resistant to an array of antibiotics, and infections by these strains are difficult to treat. In many instances, only two oral antibiotics and a very limited group of intravenous antibiotics remain effective.
Cases of tularemia, also known as “rabbit fever," are on the rise in the U.S., according to a new report from the CDC. The report identifies symptoms and the groups most at risk.
The resistance can vary from moderate to severe. Enterobacteriaceae are common commensals and infectious agents. Experts fear CRE as the new "superbug". [1] The bacteria can kill up to half of patients who get bloodstream infections. [2] Tom Frieden, former head of the Centers for Disease Control and Prevention has referred to CRE as "nightmare ...
"The mystery has finally been solved," Congo's health ministry says, after an unidentified disease outbreak started killing mainly women and children in a remote region.