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  2. Primary immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Primary_immunodeficiency

    The precise symptoms of a primary immunodeficiency depend on the type of defect. Generally, the symptoms and signs that lead to the diagnosis of an immunodeficiency include recurrent or persistent infections or developmental delay as a result of infection. Particular organ problems (e.g. diseases involving the skin, heart, facial development ...

  3. List of primary immunodeficiencies - Wikipedia

    en.wikipedia.org/wiki/List_of_primary_immuno...

    This is a list of primary immunodeficiencies (PID), which are immune deficiencies that are not secondary to another condition.. The International Union of Immunological Societies recognizes nine classes of primary immunodeficiencies, totaling approximately 430 conditions.

  4. Immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Immunodeficiency

    Primary Immunodeficiency is also known as congenital immunodeficiencies. [11] Many of these disorders are hereditary and are autosomal recessive or X-linked. There are over 95 recognised primary immunodeficiency syndromes; they are generally grouped by the part of the immune system that is malfunctioning, such as lymphocytes or granulocytes. [12]

  5. Immune disorder - Wikipedia

    en.wikipedia.org/wiki/Immune_disorder

    Severe combined immunodeficiency (SCID) DiGeorge syndrome; Hyperimmunoglobulin E syndrome (also known as Job's Syndrome) Common variable immunodeficiency (CVID): B cell levels are normal in circulation but with decreased production of IgG throughout the years, so it is the only primary immune disorder that presents onset in the late teens years.

  6. Isolated primary immunoglobulin M deficiency - Wikipedia

    en.wikipedia.org/wiki/Isolated_primary...

    Patients diagnosed with isolated primary immunoglobulin M deficiency frequently exhibit recurrent infections with common microorganisms as well as a higher incidence of autoimmune and allergy disorders. More than 80% of patients with isolated primary immunoglobulin M deficiency have recurrent infections as their presenting symptom.

  7. Common variable immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Common_variable...

    Though described in 1953, there was no standard definition for CVID until the 1990s, which caused widespread confusion during diagnosis. During the 1990s, the European Society for Immunodeficiency (ESID) and Pan-American Group for Immunodeficiency (PAGID) developed diagnostic criteria for the disease, including the minimum age of diagnosis and ...

  8. Hypogammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypogammaglobulinemia

    CVID is the most common form of primary immunodeficiency. SCID is considered a medical emergency and suspected cases require immediate specialist center referral for diagnosis and treatment. It is more often that hypogammaglobulinemia develops as a result of another condition, which are called secondary or acquired immune deficiencies.

  9. Activated PI3K delta syndrome - Wikipedia

    en.wikipedia.org/wiki/Activated_PI3K_Delta_Syndrome

    PI3kinase. The pathophysiology of activated PI3K delta syndrome has several aspects. [2] The normal function has P110δ (PI3K) involved in immune system regulation. [9]P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous ...