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Neurosyphilis is the infection of the central nervous system in a patient with syphilis. In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients. [citation needed] Meningitis is the most common neurological presentation in early syphilis.
The symptoms arise as a result of inflamed meninges, which eventually lead up to signs of meningitis. [2] Treponema pallidum invades the nervous system within three to eighteen months after the primary infection. The initial series of events is asymptomatic meningitis, which can remain in the human body system and produce more damage within the ...
Involvement of the central nervous system in syphilis (either asymptomatic or symptomatic) can occur at any stage of the infection. [21] It may occur early, being either asymptomatic or in the form of syphilitic meningitis ; or late as meningovascular syphilis, manifesting as general paresis or tabes dorsalis .
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Syphilis can attack any organ system and can cause long-term damage to the heart, brain, nerves and eyes, according to the Cleveland Clinic. Dating trends that increase STI risk
Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen. In recent years, the prevalence of syphilis has declined in Western Europe, but it has increased in Eastern Europe (former Soviet states).
Piantino is the senior author of a new study that for the first time shows how the brain’s glymphatic system clears away these proteins, emphasizing the importance of lifestyle measures such as ...
Hepatitis E, the report added, can cause severe illness, especially in those with underlying health conditions, and can lead to cirrhosis of the liver and neurological damage