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Researchers are working to determine which genetic changes may influence the risk of atrial fibrillation. [ citation needed ] Familial atrial fibrillation appears to be inherited in an autosomal dominant pattern, which means the defective gene is located on an autosome , and only one copy of the defective gene - inherited from one parent - is ...
Atrial fibrillation is associated with an increased risk of heart failure, dementia, and stroke. [3] [12] It is a type of supraventricular tachycardia. [14] Atrial fibrillation frequently results from bursts of tachycardia that originate in muscle bundles extending from the atrium to the pulmonary veins. [15]
It can have many potential causes, including genetics, lifestyle habits, and underlying health issues. Some types of cardiovascular disease, such as some cardiomyopathies, develop due to factors ...
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited genetic disorder that predisposes those affected to potentially life-threatening abnormal heart rhythms or arrhythmias. The arrhythmias seen in CPVT typically occur during exercise or at times of emotional stress, and classically take the form of bidirectional ...
For example, a meta-analysis accomplished in 2018 revealed the discovery of 70 new loci associated with atrial fibrillation. It has been identified different variants associated with transcription factor coding-genes, such as TBX3 and TBX5 , NKX2-5 o PITX2 , which are involved in cardiac conduction regulation, in ionic channel modulation and ...
Other, non-cardiovascular risk factors include obesity, diabetes, and excessive alcohol consumption. Adding to all this, there also seems to be a genetic component as well. These factors likely stress the cells in the atria, which can lead to tissue heterogeneity, which means that cells start taking on different electrical properties.