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  2. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

  3. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  4. Febuxostat - Wikipedia

    en.wikipedia.org/wiki/Febuxostat

    Febuxostat is used to treat chronic gout and hyperuricemia. [12] Febuxostat is typically recommended only for people who cannot tolerate allopurinol. [13] National Institute for Health and Clinical Excellence concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol.

  5. Anti-ulcer agents - Wikipedia

    en.wikipedia.org/wiki/Anti-ulcer_agents

    To ensure the effectiveness of the medication, patients should swallow the whole tablet. [62] They should not chew or cut the tablets, nor open the capsule and grind the granules. [62] To add on, patients should take the medicine 30 to 60 minutes before meals. [63] The chemical structure of lansoprazole.

  6. Drug rash with eosinophilia and systemic symptoms - Wikipedia

    en.wikipedia.org/wiki/Drug_rash_with_eosinophil...

    Individuals expressing the HLA allele associated with sensitivity to an indicated drug should not be treated with the drug. These recommendations include: [3] [35] Allopurinol: The American College of Rheumatology guidelines for the management of gout recommend HLA-B*58:01 screening before allopurinol treatment.

  7. Chronic prostatitis/chronic pelvic pain syndrome - Wikipedia

    en.wikipedia.org/wiki/Chronic_prostatitis/...

    For men with CPPS, taking allopurinol may give little or no difference in symptoms but also may not cause side effects. [64] Traditional Chinese medicine may not lead to side effects and may reduce symptoms for men with CPPS. However, these medicines probably don't improve sexual problems or symptoms of anxiety and depression.

  8. Severe cutaneous adverse reactions - Wikipedia

    en.wikipedia.org/wiki/Severe_cutaneous_adverse...

    Allopurinol and sulfasalazine account for almost 66% of DRESS syndrome cases with minocycline being the third most common cause of the disorder; Strontium ranelate, leflunomide, dapsone, and nonsteroidal anti-inflammatory drugs (diclofenac, celecoxib, ibuprofen, and phenylbutazone) are less common causes of the disorder.

  9. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    It is, however, not recommended if a person has a history of kidney stones. [75] Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78] Pegloticase is an option for the 3% of people who are intolerant to other medications. [79] It is a third line agent. [64]