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The virus is very common in the general population, infecting 70% to 90% of humans; most people acquire Human polyomavirus 2 in childhood or adolescence. [ 22 ] [ 23 ] [ 24 ] It is found in high concentrations in urban sewage worldwide, leading some researchers to suspect contaminated water as a typical route of infection.
Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. [1] [2] As of 2024, there are eight recognized genera. [3]Fourteen species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent.
The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV [6] similar to other cancer-causing viruses such as HPV, Epstein-Barr virus, and Hepatitis C virus [7] is a main area of research for the scientific community.
Trichodysplasia spinulosa is a proliferative skin disorder [8] [9] that occurs in immunocompromised people and is considered benign, but can be disfiguring. [10] It was suspected to be associated with viral infection on the basis of the patient population in which it appeared, and electron microscopy studies of clinical samples identified virus-like particles of a size and shape consistent ...
Water virology started about half a century ago when scientists attempted to detect the polio virus in water samples. [3] Since then, other pathogenic viruses that are responsible for gastroenteritis, hepatitis, and many other virus strains have replaced enteroviruses as the main aim for detection in the water environment.
Two additional cases of West Nile virus have been confirmed in humans in Massachusetts, as public health officials raise the risk level in 9 more cities and town.. So far this summer, there have ...