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Inositol nicotinate is generally safe when taken by mouth, but possible side effects include: Stomach upset; Intestinal gas; Nausea; Liver damage (similar to other niacin products) [1] It is marketed as "no-flush" niacin, but research suggests that the lack of flushing may be due to its limited conversion to active niacin. [4]
Laropiprant is a prostaglandin D2 binding drug shown to reduce niacin-induced vasodilation and flushing side effects. [47] [94] [95] A clinical trial showed no additional efficacy of Tredaptive in lowering cholesterol when used together with other statin drugs, but did show an increase in other side effects. [96]
Niacin products sold as "no-flush", i.e. not having side-effects such as "niacin flush", do not, however, contain free nicotinic acid and are therefore ineffective at raising HDL, while products sold as "sustained-release" may contain free nicotinic acid, but "some brands are hepatotoxic"; therefore the recommended form of niacin for raising ...
People were more likely to have quit if they had developed gastrointestinal side effects, the study found—but insurance hassles and expenses may also be factors, since the drugs can cost more ...
Experts agree that eating wholesome, healthy meals, reducing calories, and increasing physical activity are the best ways to lose weight and keep it off long-term. Still, many people turn to ...
Ozempic before and after photos show weight loss. Women share what it's like to lose weight with Ozempic and Wegovy, the side effects and cost. ... 5 women get real about weight loss, side effects ...