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Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
However, the spermicide nonoxynol-9 is itself associated with increased risk of UTI, yeast infection, and bacterial vaginosis. [23] For this reason, some advocate use of lactic acid or lemon juice based spermicides, which might have fewer side effects. [24]
People sensitive to Nonoxynol-9, an ingredient in the spermicide used in the sponge, may experience unpleasant irritation and may face increase risk of sexually transmitted infections. Sponge users may have a slightly higher risk of toxic shock syndrome. [6]
Nonoxynol-9 and other kinds of spermicide would be less potent after an expiration date, which could lead to unwanted pregnancy. Lube also has some unusual uses outside the bedroom
The most common active ingredient of spermicides is nonoxynol-9. Spermicides containing nonoxynol-9 are available in many forms, such as jelly (gel), films, and foams. Used alone, spermicides have a perfect use failure rate of 6% per year when used correctly and consistently, and 16% failure rate per year in typical use. [1]
The Today sponge is a brand of plastic contraceptive sponge saturated with a spermicide nonoxynol-9 to prevent conception. [1] While initially popular in the 1980s in the United States, it is no longer commercially available as of 2019.
Nonoxynol-9, a spermicide, is ineffective as a topical microbicide in preventing HIV infection. Although nonoxynol-9 has been shown to increase the risk of HIV infection when used frequently by women at high risk of infection, it remains a contraceptive option for women at low risk. [27]
The most commonly discussed compound nonoxynol-9 is a spermicide, formulated primarily as a component of vaginal foams and creams. Nonoxynol was found to metabolize into free nonylphenol when administered to lab animals. [1] Arkopal-N60, with on average 6 ethylene glycol units is a related used surfactant.