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  2. Indapamide - Wikipedia

    en.wikipedia.org/wiki/Indapamide

    Indapamide has been shown to reduce stroke rates in people with high blood pressure. [7] [11] [12] Studies have shown that the blood pressure lowering effects of indapamide in combination with perindopril reduce the rate of stroke in high risk patients (those with a history of high blood pressure, stroke or type two diabetes).

  3. Perindopril/indapamide - Wikipedia

    en.wikipedia.org/wiki/Perindopril/indapamide

    Using a fixed combination of an ACE inhibitor and a chlorosulfamoyl diuretic leads to additive synergy of the antihypertensive effects of the two constituents. Its pharmacological properties are derived from those of each of the components taken separately, in addition to those due to the additive synergistic action of the two constituents, when combined, on vascular endothelium ...

  4. Perindopril - Wikipedia

    en.wikipedia.org/wiki/Perindopril

    Each tablet contains 2, 4, or 8 mg of the tert-butylamine salt of perindopril. Perindopril is also available under the trade name Coversyl Plus, containing 4 mg of perindopril combined with 1.25 mg indapamide, a thiazide-like diuretic. In Australia, each tablet contains 2.5, 5, or 10 mg of perindopril arginine.

  5. Ramipril - Wikipedia

    en.wikipedia.org/wiki/Ramipril

    Common side effects include headaches, dizziness, fatigue, and cough. [1] Serious side effects may include liver problems, angioedema, kidney problems, and high blood potassium. [1] Use in pregnancy and breastfeeding is not recommended. [5] It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity. [1]

  6. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [ 5 ] [ 65 ] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke , and 5 cases of muscle damage per 10,000 people treated. [ 34 ]

  7. Nebivolol - Wikipedia

    en.wikipedia.org/wiki/Nebivolol

    Common side effects include dizziness, feeling tired, nausea, and headaches. [6] Serious side effects may include heart failure and bronchospasm. [6] Its use in pregnancy and breastfeeding is not recommended. [5] [7] It works by blocking β1-adrenergic receptors in the heart and dilating blood vessels. [6] [8]

  8. Osteoarthritis - Wikipedia

    en.wikipedia.org/wiki/Osteoarthritis

    Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]

  9. Sleep deprivation - Wikipedia

    en.wikipedia.org/wiki/Sleep_deprivation

    The negative effects of sleep deprivation on alertness and cognitive performance suggest decreases in brain activity and function. These changes primarily occur in two regions: the thalamus, a structure involved in alertness and attention, and the prefrontal cortex, a region subserving alertness, attention, and higher-order cognitive processes ...