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A stem cell possesses two properties: . Self-renewal is the ability to go through numerous cycles of cell division while still maintaining its undifferentiated state. Stem cells can replicate several times and can result in the formation of two stem cells, one stem cell more differentiated than the other, or two differentiated cells.
Cell potency is a cell's ability to differentiate into other cell types. [1] [2] The more cell types a cell can differentiate into, the greater its potency.Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally ...
Pluripotent adult stem cells are rare and generally small in number, but they can be found in umbilical cord blood and other tissues. [49] Bone marrow is a rich source of adult stem cells, [50] which have been used in treating several conditions including liver cirrhosis, [51] chronic limb ischemia [52] and endstage heart failure. [53]
Neural stem cells differentiating to astrocytes (green) and sites of growth hormone receptor shown in red. There are two basic types of stem cell: adult stem cells, which are limited in their ability to differentiate, and embryonic stem cells (ESCs), which are pluripotent and have the capability of differentiating into any cell type.
Cell-count distribution featuring cellular differentiation for three types of cells (progenitor , osteoblast , and chondrocyte ) exposed to pro-osteoblast stimulus. [1] Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one. [2][3] Usually, the cell changes to a more specialized type.
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka and Kazutoshi Takahashi in Kyoto, Japan, who together showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2 ...
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