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Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells. [11] IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor which is expressed in various types of cells, including keratinocytes in ...
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." If you're human you've likely had a pimple on your nose, but what's more annoying than a pimple on ...
The history of psoriasis is littered with treatments of dubious effectiveness and high toxicity. In the 18th and 19th centuries, Fowler's solution, which contains a poisonous and carcinogenic arsenic compound, was used by dermatologists as a treatment for psoriasis. [135] Mercury was also used for psoriasis treatment during this time. [135]
However, today the treatment can be done with reduced cost as an outpatient. It has been stated by de Miguel et al., that an annual three-week outpatient course of Goeckerman treatment costs $10,000 to 12,000 but repeat treatment may be extended to two years with the use of a $2,000 home UVB treatment lamp . [ 6 ]
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