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Colloids contain larger insoluble molecules, such as gelatin; blood itself is a colloid. There is no evidence that colloids are better than crystalloids in those who have had trauma, burns, or surgery. Colloids are more expensive than crystalloids. As such, colloids are not recommended for volume expansion in these settings. [2]
Ideally, this is achieved by isovolemia exchange transfusion of a plasma substitute with a colloid osmotic pressure (OP). A colloid is a fluid containing particles that are large enough to exert an oncotic pressure across the micro-vascular membrane. When debating the use of colloid or crystalloid, it is imperative to think about all the ...
Plasma-Lyte is a crystalloid solution for intravenous infusion, with varying electrolyte formulation depending on market. Generally the solution has a composition that mimics human physiological plasma electrolyte concentrations, osmolality and pH. [1] It is available as a generic medication. [2] [3]
Ringer's lactate solution is in the crystalloid family of medications. [5] It is isotonic, i.e. it has the same tonicity as blood. [2] Ringer's solution was invented in the 1880s; lactate was added in the 1930s. [4] It is on the World Health Organization's List of Essential Medicines. [6] Lactated Ringer's is available as a generic medication. [1]
A colloidal crystal is an ordered array of colloidal particles and fine grained materials analogous to a standard crystal whose repeating subunits are atoms or molecules. [1] A natural example of this phenomenon can be found in the gem opal, where spheres of silica assume a close-packed locally periodic structure under moderate compression.
[22] [23] This characteristic can allow for recovery of initial state through an external stimulus, which is often exploited in research. [24] [25] Self-assembly is an inherent characteristic of soft matter systems. The characteristic complex behavior and hierarchical structures arise spontaneously as a system evolves towards equilibrium. [20]
Gelofusine is a volume expander that is used as a blood plasma replacement if a significant amount of blood is lost due to extreme hemorrhaging, trauma, dehydration, or a similar event. [1] Gelofusine is a 4% w/v solution of succinylated gelatine (also known as modified fluid gelatine) used as an intravenous colloid , and behaves much like ...
Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.The use of HES on critically ill patients is associated with an increased risk of death and kidney problems.