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Multiple sclerosis can cause a variety of symptoms including changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, impaired movement, difficulties with coordination and balance, problems in speech (known as dysarthria) or swallowing , visual problems (nystagmus, optic neuritis, or diplopia), fatigue and acute or chronic ...
The patient has fever, joint pain, and erythema that can be soothed with the use of steroids and analgesics. Urticaria (hives) can also be present. It is possible to diminish their toxicity by using highly purified serum fractions and intravenous administration in the combination with other immunosuppressants, for example, calcineurin ...
[5] [7] As of 2021, the online version stays divided into two parts, in the same way as the 2006 edition, and includes updates on shingles and COVID-19. [ 6 ] [ 8 ] [ 9 ] According to Andrew Pollard , The Green Book should be "bookmarked" in all child clinics and notes that similar information can be obtained from the US Centers for Disease ...
The McDonald criteria are diagnostic criteria for multiple sclerosis (MS). These criteria are named after neurologist W. Ian McDonald who directed an international panel in association with the National Multiple Sclerosis Society (NMSS) of America and recommended revised diagnostic criteria for MS in April 2001.
Immunosuppression is a reduction of the activation or efficacy of the immune system.Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.
The Patient Reported Outcome Indices for Multiple Sclerosis (PRIMUS) is a disease specific patient-reported outcome questionnaire which measures the quality of life (QoL) of patients with multiple sclerosis. [1] The measure contains an assessment of quality of life, activity limitations and symptoms.
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Multiple sclerosis diagnosis can only be made when there is proof of lesions disseminated in time and in space. Therefore, when damage in the CNS is big enough to be seen. It would be desirable to make it faster. The ideal diagnosis schema would be able to determine for any given subject, if he will develop MS, at any point in his life, and when.
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