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  2. A Comprehensive Guide to Navigating Your Dog’s Pregnancy - AOL

    www.aol.com/comprehensive-guide-navigating-dog...

    The “heat season” begins around 6 months of age, on average, for unspayed female dogs. ... Being in heat sends a biological signal to any curious male, and often during her cycle, a female dog ...

  3. Estrous cycle - Wikipedia

    en.wikipedia.org/wiki/Estrous_cycle

    Female dogs bleed during estrus, which usually lasts from 7–13 days, depending on the size and maturity of the dog. Ovulation occurs 24–48 hours after the luteinizing hormone peak, which occurs around the fourth day of estrus; therefore, this is the best time to begin breeding.

  4. Canine reproduction - Wikipedia

    en.wikipedia.org/wiki/Canine_reproduction

    During proestrus and estrus, females may have a clear, blood tinged, or bloody discharge. Dogs during these stages are often informally referred to as being in heat. The length of these cycles varies greatly among breeds and even between individuals of the same breed. Proestrus and estrus can last anywhere from 5 days to 21 days. [5] 3.

  5. Hypothalamic–pituitary–gonadal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Evolutionarily speaking, this makes sense as it is unwise for the body to spend excess energy that it does not have to grow the body larger. Additionally, the effects of these hormones on GnRH secretion can vary depending on the stage of the estrous cycle, nutritional status, and other physiological factors.

  6. Mibolerone - Wikipedia

    en.wikipedia.org/wiki/Mibolerone

    Mibolerone, also known as dimethylnortestosterone (DMNT) and sold under the brand names Cheque Drops and Matenon, is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was marketed by Upjohn for use as a veterinary drug.

  7. Induced ovulation (animals) - Wikipedia

    en.wikipedia.org/wiki/Induced_ovulation_(animals)

    The natural cycle of spontaneous ovulation occurs in species such as cows. [21] There is a great demand for ovulation to be induced in cattle, as it allows farmers to synchronize their cattle to ovulate at the same time, helping improve the efficiency of dairy farming. [ 22 ]

  8. Cortisol - Wikipedia

    en.wikipedia.org/wiki/Cortisol

    Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone.When used as medication, it is known as hydrocortisone.. It is produced in many animals, mainly by the zona fasciculata of the adrenal cortex in an adrenal gland. [1]

  9. Progesterone - Wikipedia

    en.wikipedia.org/wiki/Progesterone

    The metabolic clearance rate of a steroid is defined as the volume of blood that has been completely cleared of the hormone per unit time. The production rate of a steroid hormone refers to entry into the blood of the compound from all possible sources, including secretion from glands and conversion of prohormones into the steroid of interest ...