Ads
related to: sickle cell ethnicity- Safety and Side Effects
Review the Safety Profile
And Potential Side Effects.
- Treatment Journey
Learn More About Treatment And
See If It's Right for Your Patients
- HCP Resources
Download Treatment Brochures,
Billing Codes, and More.
- Mechanism of Action
See How Gene Therapy Works.
Learn the Science Behind Treatment
- Important Safety Info
View Warnings And Precautions.
Understand the Potential Risks.
- Prescribing Information
View Full Prescribing Information &
Indications And Usage.
- Safety and Side Effects
Search results
Results From The WOW.Com Content Network
Sickle cell disease is common in some ethnic groups of central India, [168] where the prevalence has ranged from 9.4 to 22.2% in endemic areas of Madhya Pradesh, Rajasthan, and Chhattisgarh. [169] It is also endemic among Tharu people of Nepal and India; however, they have a sevenfold lower rate of malaria despite living in a malaria infested ...
Autosomal dominant A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous (carrier) condition. [1]
(2011), "Organized Ambivalence: When Stem Cell Research & Sickle Cell Disease Converge". Ethnicity & Health, Vol. 16, Issue 4–5: 447–463. (2012). "Genetics and Global Public Health: Sickle Cell and Thalassaemia". Ch. 11 in Simon Dyson and Karl Atkin (eds), Organized Ambivalence: When Stem Cell Research & Sickle Cell Disease Converge ...
This would be similar to the hemoglobin allele which is responsible for sickle-cell disease, but solely in people with two copies; those with just one copy of the allele have a sickle cell trait and gain partial immunity to malaria as a result. This effect is called heterozygote advantage. [27]
Thus, people of African and Mediterranean descent are found to be more susceptible to sickle-cell disease while cystic fibrosis and hemochromatosis are more common among European populations. [54] Some physicians claim that race can be used as a proxy for the risk that the patient may be exposed to in relation to these diseases.
Sickle cell disease disproportionately impacts Black individuals, and research on the condition has been underfunded for years. The Sickle Cell Disease Association of America is dedicated to ...
Red cell alloimmunisation is common in people with sickle cell disease who receive transfusions in Europe and North America. [4] This is because there are ethnic differences in the frequencies of blood group antigens. [4] Blood donors are usually Caucasian whereas the blood transfusion recipients usually have an African or Afro-Caribbean ancestry.
For example, people of African American ethnicity have a much higher likelihood of being a carrier for the autosomal recessive disorder called sickle cell anemia. [3] People of one ethnicity in particular, Ashkenazi Jewish, have a tendency to be carriers for a wide variety of recessive genetic disorders. There are also several recessive ...
Ad
related to: sickle cell ethnicity