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Muir–Torre syndrome is a rare hereditary, autosomal dominant cancer syndrome [1]: 663 that is thought to be a subtype of HNPCC (Lynch syndrome). Individuals are prone to develop cancers of the colon, genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumors .
Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]
Other SGc including those occurring outside of the head and neck region and the presentation of multiple at a time are believed to be associated with genetic defects including defects in mismatch repair genes, Muir–Torre syndrome (MTS), and familial retinoblastoma. [11] [10] [9]
Ferguson–Smith syndrome + Muir–Torre syndrome + + Nevoid basal cell carcinoma syndrome + Bazex syndrome + Rombo syndrome + Discoid lupus erythematosus + Erosive lichen planus + Lichen sclerosus + Porokeratosis + Nevus sebaceous [note 1] + Chronic non-healing wounds + Seborrheic keratosis +
Sebaceous adenoma, a benign slow-growing tumour—which may, however, in rare cases be a precursor to a cancer syndrome known as Muir–Torre syndrome. [5] Sebaceous carcinoma, an uncommon and aggressive cutaneous tumour. [37]
Most painful of all was the loss of her family photos, including those of her late son, Tommy, who died at 12 years old. The precious photographs of him had been a cherished memory.
There have been no shortage of wardrobe malfunctions in 2017, and we have stars like Bella Hadid, Chrissy Teigen and Courtney Stodden to thank for that.
Sebaceoma is a smooth-bordered, plump, well-circumscribed benign tumor that may expand into the subcutis, middle dermis, and deep dermis. Lesions range in size from tiny lesions to 20 mm. Clinically, the tumor appears as a single flesh-colored or erythematous nodule or plaque in the head and neck region.