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Sebaceous adenomais a type of adenoma, characterized by a slow-growing tumor usually presenting as a pink, flesh-coloured, or yellow papule or nodule. [ 1 ] : 662 [ 2 ] Significance
Adenoma sebaceum presence represents one of the major diagnostic criteria to confirm the diagnosis of tuberous sclerosis. [5] When adenoma sebaceum presents with seizures and mental retardation (Vogt's triad), it indicates that cranial imaging is necessary, other differential diagnoses for this disorder include acne vulgaris, rhinophyma, and sebaceous hyperplasia.
Muir–Torre syndrome is a rare hereditary, autosomal dominant cancer syndrome [1]: 663 that is thought to be a subtype of HNPCC (Lynch syndrome). Individuals are prone to develop cancers of the colon, genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumors.
Sebaceoma is a smooth-bordered, plump, well-circumscribed benign tumor that may expand into the subcutis, middle dermis, and deep dermis. Lesions range in size from tiny lesions to 20 mm. Clinically, the tumor appears as a single flesh-colored or erythematous nodule or plaque in the head and neck region.
Sebaceous hyperplasia primarily affects older patients in areas with high concentrations of sebaceous glands, such as the face, head, and neck. [3] It typically manifests as yellowish-colored skin with small papules that are often surrounded by telangiectatic blood vessels, also known as "crown vessels," and a central dell that is in line with the origin of the lesions, which is a dilated ...
The distinction may be moot because both entities have the same treatment, although the adenoma has a greater growth potential. Sebaceous carcinoma of the oral cavity has been reported, presumably arising from Fordyce granules or hyperplastic foci of sebaceous glands. [citation needed]
In rare cases, tumors can be deemed inoperable due to their size and location under vital structures of the face. Chemotherapy and radiation treatment have been used when metastasis has occurred or when an excision cannot be performed, [7] but results have been inconclusive about their effectiveness. In some cases, radiation therapy has been ...
Fibrous papules are also termed facial angiofibromas and were formerly and incorrectly termed adenoma sebaceum (fibrous papules are unrelated to sebaceous glands [4]). They develop in up to 8% of the general adult population and occur as 1 to 3 [5] pink to red, [4] dome-shaped papules in the central areas of the face, nose, and/or lips. [6]