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[5] [6] [7] The study's authors estimated that the number needed to treat with rosuvastatin to prevent one cardiovascular event was 95 over two years, extrapolated to 25 over five years. The trial was stopped early, after just 1.9 years median duration, by the study's Independent Data Monitoring Board, because the interim results met the study ...
The findings show a decrease in mortality among people 60 years of age and older — including people over the age of 85 — who took statins. The study is published in Annals of Internal Medicine .
Reaching and maintaining target LDL cholesterol levels was lower in women than in men. ... The authors noted that over a 21-year period, women were diagnosed later than men for more than 700 ...
A 2010 review concluded that treatment without history of cardiovascular disease reduces cardiovascular events in men but not women, and provides no mortality benefit in either sex. [27] Two other meta-analyses published that year, one of which used data obtained exclusively from women, found no mortality benefit in primary prevention. [28] [29]
According to the Reader’s Digest survey, half of women agreed that “statins can be difficult to tolerate,” compared with just 36% of men. More than one third of women believe that doctors ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.