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The drug's mode of action is not exactly known at present, but experimental evidence indicates praziquantel increases the permeability of the membranes of schistosome cells towards calcium ions. The drug thereby induces contraction of the parasites' muscle, resulting in paralysis in the contracted state.
Unfortunately, not much information is available on this for several of those medications in dogs. In human medicine, we do know that some drugs are contraindicated when giving ivermectin (1).
This article lists veterinary pharmaceutical drugs alphabetically by name. Many veterinary drugs have more than one name and, therefore, the same drug may be listed more than once. Abbreviations are used in the list as follows: INN = International Nonproprietary Name; BAN = British Approved Name; USAN = United States Adopted Name
Treatment protocol will vary based on the dog's age, production level and activity level. There are different treatment paths for puppies, pregnant bitches, lactating bitches, dogs with increased risk of infection, professional dogs, and dogs sharing homes with young children or immunocompromised individuals.
Drug administration via the nasal cavity yields rapid drug absorption and therapeutic effects. [33] This is because drug absorption through the nasal passages does not go through the gut before entering capillaries situated at tissue cells and then systemic circulation and such absorption route allows transport of drugs into the central nervous ...
Orally administered contraception for dogs and cats became available in Europe in 1963, followed by the US in the 1970s. [4] [5] The initial products were mostly progestin-based treatments implemented for sterilization. One of the first drugs sold was medroxyprogesterone acetate (MPA).
Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]
The interaction between the drug and this site results in a modification of the target that may include inhibition or potentiation. [15] Most of the pharmacogenetic interactions that involve drug targets are within the field of oncology and include targeted therapeutics designed to address somatic mutations (see also Cancer Pharmacogenomics).