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Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Scientists have proven that intralesional injection of autologous bone marrow stem cells is a safe and effective treatment modality in oral submucosal fibrosis. It has been shown autologous bone marrow stem cell injections induces angiogenesis in the lesion area, which in turn decreases the extent of fibrosis, thereby leading to significant ...
"Graft-vs.-host disease-like": Widespread lichenoid eruption with severe mucous membrane involvement "Lichen planus-like": Small red flat-topped scaly papules; It is most common that mucous membrane lesions of the oral cavity are presented first. They can involve the oropharynx, nasopharynx, tongue, and vermilion (red portion) of the lips.
A lichenoid eruption is a skin disease characterized by damage and infiltration between the epidermis and dermis. [1] Examples include lichen planus, lichen sclerosus and lichen nitidus. It can also be associated with abrasion or drug use. [2]
Lichenoid eruptions are dermatoses related to the unique, common inflammatory disorder lichen planus, which affects the skin, mucous membranes, nails, and hair. [74] [75] [76] Annular lichen planus Lichen planus actinicus; Atrophic lichen planus; Bullous lichen planus (vesiculobullous lichen planus) Erosive lichen planus
Leukoplakia could be classified as mucosal disease, and also as a premalignant condition. Although the white color in leukoplakia is a result of hyperkeratosis (or acanthosis ), similarly appearing white lesions that are caused by reactive keratosis ( smoker's keratosis or frictional keratoses e.g. morsicatio buccarum ) are not considered to be ...
Persistent blood clots can lead to congestive blood flow in bone marrow, impaired blood flow and ischaemia in bone tissue resulting in lack of oxygen , bone cell damage and eventual cell death . Of significance is the fact that the average concentration of cadmium in human bones in the 20th century has increased to about 10 times above the pre ...
The side effects of corticosteroids may require the use of so-called steroid-sparing or adjuvant drugs. One of the most dangerous side effects of high-dosage steroid treatments is intestinal perforations, [citation needed] which may lead to sepsis. Steroids and other medications being taken to treat pemphigus may also mask the effects of the ...