Ad
related to: single strand rna binding protein review youtube
Search results
Results From The WOW.Com Content Network
Differing from the CCHH-type, the CCCH-type zinc finger displays another mode of RNA binding, in which single-stranded RNA is identified in a sequence-specific manner. Overall, zinc fingers can directly recognize DNA via binding to dsDNA sequence and RNA via binding to ssRNA sequence. [12]
In ICP8, the herpes simplex virus (HSV-1) single-strand DNA-binding protein (ssDNA-binding protein (SSB)), the head consists of the eight alpha helices.The front side of the neck region consists of a five-stranded beta-sheet and two alpha helices, whereas the back side is a three-stranded beta-sheet The shoulder part of the N-terminal domain contains an alpha-helical and beta-sheet region. [1]
The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs in the N-terminal domain which are pivotal for RNA specificity and binding. The protein also has a glycine rich arginine-glycine-glycine (RGG) region called the RGG box which enables protein and RNA binding. It affects many critical genes that are ...
Start with single-stranded RNA, and create a pattern of stem-loop structures by adding copies of the MS2 RNA-binding sequences to a noncoding region. [5] The MS2 protein must be fused with GFP and bonded to an mRNA, a complex that contains the MS2’s RNA-binding sequence copies. [5]
RNA expression pattern; Bgee: Human ... Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene. [5] [6]
But only one of the two single-stranded RNA here will be utilized to base pair with target mRNA. It is known as the guide strand, which is incorporated into the Argonaute protein and leads gene silencing. The other single-stranded RNA, named the passenger strand, is degraded during the RNA-induced silencing complex process. [7]
In mRNA degradation, ribonuclease E recognizes and cleaves the single-stranded RNA in A- and U-rich regions. [9] The RNase E catalytic domain binds selectively to 5′-monophosphate RNA termini but has a mode of cleavage in the 3′ to 5′ direction. RNase E can identify cleavage sites by a 3′ to 5′ scanning mechanism. [17]
The protein encoded by this gene appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA ...