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As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight U.S. adults takes antidepressants—scientists have been innovating novel treatments for it.
A new medication called Auvelity was just FDA-approved to treat major depressive disorder (MDD), also known as clinical depression, in as little as one week. The new “fast-acting” oral drug ...
The reality is, roughly 21 million adults in the U.S. experienced a major depressive episode in 2021. There’s good news, though. Depression is highly treatable.
Aticaprant, also known by its developmental codes JNJ-67953964, CERC-501, and LY-2456302, is a κ-opioid receptor (KOR) antagonist which is under development for the treatment of major depressive disorder. [2] [3] [4] A regulatory application for approval of the medication is expected to be submitted by 2025. [2] Aticaprant is taken by mouth. [1]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
The World Health Organisation has stated that depression is a leading cause of disability worldwide and a major contributor to the global burden of disease. [5] Stephen Ilardi has described depression as a "disease of civilisation", stating "We were never designed for the sedentary, indoor, sleep-deprived, socially-isolated, fast-food-laden, frenetic pace of modern life".
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