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Mitochondrial uncoupling protein 2 is a protein that in humans is encoded by the UCP2 gene. [ 5 ] Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP).
An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter. An uncoupling protein is thus capable of dissipating the proton gradient generated by NADH -powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space.
An uncoupler or uncoupling agent is a molecule that disrupts oxidative phosphorylation in prokaryotes and mitochondria or photophosphorylation in chloroplasts and cyanobacteria by dissociating the reactions of ATP synthesis from the electron transport chain.
Mitochondrial uncoupling protein 3 (UCP3) is a members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and transfer of protons from the outer to the inner mitochondrial membrane, reducing the mitochondrial membrane potential in mammalian cells.
Uncoupling or uncouple may refer to: Uncoupling (neuropsychopharmacology), changes in neurochemical binding sites as a consequence of drug tolerance. An uncoupling protein in cell biology. An uncoupling agent in cell biology. Uncoupling (or decoupling) rail vehicles.
Coupling with oxidative phosphorylation is a key step for ATP production. However, in specific cases, uncoupling the two processes may be biologically useful. The uncoupling protein, thermogenin—present in the inner mitochondrial membrane of brown adipose tissue—provides for an alternative flow of protons back to the inner mitochondrial ...
2 Characteristics of thermogenic plants. 3 Examples. 4 Heat production. ... Alternative oxidase and uncoupling proteins similar to those found in mammals enable the ...
This can occur since an alternative return route for the protons exists through an uncoupling protein in the inner membrane. This protein, known as uncoupling protein 1 ( thermogenin ) - which is unique to brown adipose tissue, [ 21 ] facilitates the return of the protons after they have been actively pumped out of the mitochondrial matrix by ...