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The mesothelium is a membrane composed of simple squamous epithelial cells of mesodermal origin, [2] which forms the lining of several body cavities: the pleura (pleural cavity around the lungs), peritoneum (abdominopelvic cavity including the mesentery, omenta, falciform ligament and the perimetrium) and pericardium (around the heart).
Schematic diagram of an organ invaginating into a serous cavity. The pericardial cavity (surrounding the heart), pleural cavity (surrounding the lungs) and peritoneal cavity (surrounding most organs of the abdomen) are the three serous cavities within the human body. While serous membranes have a lubricative role to play in all three cavities ...
Cytology of normal mesothelium, with typical features. Wright's stain. The lateral plate mesoderm splits into the parietal (somatic) and visceral (splanchnic) layers. The formation of these layers starts with the appearance of intercellular cavities. [12] The somatic layer depends upon a continuous layer with mesoderm that covers the amnion.
A germ layer is a collection of cells, formed during animal and mammalian embryogenesis.Germ layers are typically pronounced within vertebrate organisms; however, animals or mammals more complex than sponges (eumetazoans and agnotozoans) produce two or three primary tissue layers.
Mesothelin is a 40 kDa protein that is expressed in mesothelial cells. [7] The protein was first identified by its reactivity with monoclonal antibody K1. [8] Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named ...
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue.
Normal histology of the breast, with basement membrane annotated near center-right. Prostate gland microanatomy, with basement membrane annotated at bottom.. As seen with the electron microscope, the basement membrane is composed of two layers, the basal lamina and the reticular lamina. [4]
The surface of the ovaries is covered with a membrane consisting of a lining of simple cuboidal-to-columnar shaped mesothelium, [7] called the germinal epithelium. Micrograph of the ovarian cortex from a rhesus monkey showing several round follicles embedded in a matrix of stromal cells. A secondary follicle sectioned through the nucleus of an ...