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The name rhesus factor (Rh) goes back to the use of erythrocytes extracted from the blood of rhesus monkeys for obtaining the first blood serum. The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is most likely to be involved in transfusion reactions.
When Wiener and Landsteiner discovered the Rh factor in 1937 (named after the Rhesus monkeys used as test subjects), they did not immediately realize its significance. It was seen as yet another factor, not much different from the M, N, or P factors—useful for "fingerprinting," but not having much more extended implications.
Rh disease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the fetus and newborn (HDFN). HDFN due to anti-D antibodies is the proper and currently used name for this disease as the Rh blood group system actually has more than 50 antigens and not only the ...
In 1937, with Alexander S. Wiener, he identified the Rhesus factor, thus enabling physicians to transfuse blood without endangering the patient's life. With Constantin Levaditi and Erwin Popper, he discovered the polio virus in 1909. He received the Aronson Prize in 1926. In 1930, he received the Nobel Prize in Physiology or Medicine.
Bruce Chown [pronunciation?] OC MC FRSC (/t͡ʃaʊn/; November 10, 1893 – July 3, 1986) was a Canadian medical doctor who researched the blood factor known as the Rhesus factor and discovered an Rh immune vaccine, Rh gamma globulin, which helps to prevent Erythroblastosis fetalis.
Neva Irene Martin Abelson (November 19, 1910 – September 26, 2000) [1] was a distinguished research physician who co-discovered the life-saving blood test for the Rh blood factor (with Louis K. Diamond). The Philip and Neva Abelson Hall at Washington State University was named in her honor. [2]
Rh blood group, D antigen also known as Rh polypeptide 1 (RhPI) or cluster of differentiation 240D (CD240D) is a protein that in humans is encoded by the RHD gene. [5]The RHD gene codes for the RhD erythrocyte membrane protein that is the Rh factor antigen of the Rh blood group system. [6]
Beyond Moore's study of Rh and MN blood types, she also discovered in a group of 2496 African Americans that 51.94% of them were in Group O, 17.32% in Group B, only 27.3% were in Group A, and 3.01% in AB.