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A spasm is a sudden involuntary contraction of a muscle, [1] a group of muscles, or a hollow organ, such as the bladder. A spasmodic muscle contraction may be caused by many medical conditions, including dystonia .
A cramp is a sudden, involuntary, painful skeletal muscle contraction [1] [2] or overshortening associated with electrical activity; [3] while generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affected muscle.
Benign fasciculation syndrome (BFS) is characterized by fasciculation (twitching) of voluntary muscles in the body. [1] The twitching can occur in any voluntary muscle group but is most common in the eyelids, arms, hands, fingers, legs, and feet.
The depolarizing neuromuscular blocker succinylcholine causes fasciculations. It is a normal side effect of the drug's administration, and can be prevented with a small dose of a nondepolarizing neuromuscular blocker prior to the administration of succinylcholine, often 10% of a nondepolarizing NMB's induction dose.
Cramp fasciculation syndrome (CFS) is a rare [1] peripheral nerve hyperexcitability disorder. It is more severe than the related (and common) disorder known as benign fasciculation syndrome; it causes fasciculations, cramps, pain, fatigue, and muscle stiffness similar to those seen in neuromyotonia (another related condition). [2]
Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular.. Myoclonus (myo-"muscle", clonus "spasm") describes a medical sign and, generally, is not a diagnosis of a dis
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