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This is an accepted version of this page This is the latest accepted revision, reviewed on 29 December 2024. Polycyclic organic compound having sterane as a core structure This article is about the family of polycyclic compounds. For the drugs, also used as performance-enhancing substances, see Anabolic steroid. For the scientific journal, see Steroids (journal). For the Death Grips EP, see ...
Gonane is a tetracyclic hydrocarbon with no double bonds. It is formally the parent compound of the steroids, hence it is called the "steroid nucleus". [1] [4] [5] Some important gonane derivatives are the steroid hormones, characterized by methyl groups at the C10 and C13 positions and a side chain at the C17 position.
Removal of the ketone at the C3 position can dramatically decrease AR agonist activity but render the steroid into an androgen prohormone. Examples: ethylestrenol, bolenol, desoxymethyltestosterone. Aromatization of the A ring abolishes AR affinity and produces estrogenicity.
Sterols are a subgroup of steroids with a hydroxyl group at the 3-position of the A-ring. [10] They are amphipathic lipids synthesized from acetyl-coenzyme A via the HMG-CoA reductase pathway. The overall molecule is quite flat. The hydroxyl group on the A ring is polar. The rest of the aliphatic chain is non-polar.
A secosteroid (/ ˈ s ɛ k oʊ ˌ s t ɛ r ɔɪ d /) is a type of steroid with a "broken" ring. The word secosteroid derives from the Latin verb secare meaning "to cut", [2]: 241 and 'steroid'. Secosteroids are described as a subclass of steroids under the IUPAC nomenclature. [1]: §3S-1 [3] Some sources instead describe them as compounds ...
Steroids feature a cucurbitane core, although in practice they are biosynthesised from either lanosterol (animals and fungi) or cycloartenol (plants) via the cyclization of squalene. Steroids have two principal biological functions, being either key components of cell membranes or signaling molecules that activate steroid hormone receptors.
Stenbolone (2-methyl-δ 1-DHT) Never marketed 1-Testosterone (dihydroboldenone; δ 1-DHT) Mesabolone (a 17-ether prodrug of δ 1-DHT) Prostanozol (a 17-ether prodrug of 17α-demethylstanozolol) 17α-Alkylated derivatives. Marketed Androisoxazole (an isoxazole A ring-fused derivative of 17α-methyl-DHT) Furazabol (a furan A ring-fused derivative ...
This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives. Androgen esters are mostly not included in this list. The major classes of testosterone derivatives include the following (as well as combinations thereof):