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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Stiff-person syndrome — often called SPS — is a rare autoimmune disorder, meaning that infection-fighting cells in the body mistakenly attack healthy tissues.
What is Stiff Person Syndrome? Francesca Casonato. May 26, 2023 at 10:54 AM. Celine Dion canceled the rest of her world tour following her diagnosis of an incurable neurological condition.
Celine Dion says stiff person syndrome is causing spasms that are affecting her singing. Here's what to know about the rare disorder and why it's so serious.
Celine Dion revealed her diagnosis with stiff person syndrome in December 2022 before canceling her upcoming tour dates indefinitely in May 2023. In December 2023, ...
Restless legs syndrome: Central nervous system (thought to involve dopaminergic pathways) Unknown Uncertain 5-15% (more common in older adults) [67] Stiff-person syndrome: Central nervous system Anti-GAD, anti-amphiphysin Confirmed Rare [68] Sydenham's chorea: Brain Anti-basal ganglia Confirmed Rare (linked to Group A streptococcal infection) [69]
For those with the rare health condition, which causes uncontrollable muscle spasms, daily life is challenging without help and treatment.
5-year survival rate of 10% [2] Amyloid cardiomyopathy ( stiff heart syndrome ) [ 5 ] is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the systemic production and release of many amyloidogenic proteins , especially immunoglobulin light chain or transthyretin (TTR). [ 6 ]