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One of his studies involved feeding live hepatitis virus from others stool samples to sixty healthy children. Krugman watched as their skin and eyes turned yellow and their livers got bigger. He watched them vomit and refuse to eat. All the children fed hepatitis virus became ill, some severely.
Under his direction, a number of children with intellectual disabilities were intentionally infected with hepatitis A at the Willowbrook State School. [6] According to the celebrated vaccinologist Maurice Hilleman, "They [the Willowbrook studies] were the most unethical medical experiments ever performed on children in the United States." [7]
His study became instrumental in the implementation of federal rules on human experimentation and informed consent. [ 6 ] [ 7 ] [ 8 ] Beecher's study listed over 20 cases of mainstream research where subjects were subject to experimentation without being fully informed of their status as research subjects, and without knowledge of the risks of ...
From the 1950s to 1972, mentally disabled children at the Willowbrook State School in Staten Island, New York, were intentionally infected with viral hepatitis, for research whose purpose was to help discover a vaccine. [48]
Robert Wayne McCollum Jr. (January 29, 1925 – September 13, 2010) was an American virologist and epidemiologist who made pioneering studies into the nature and spread of polio, hepatitis and mononucleosis while at the Yale School of Medicine, after which he served for nearly a decade as Dean of the Dartmouth Medical School.
William Bronston (born March 1939) is an American physician and activist known for his involvement in the deinstitutionalization of Willowbrook State School in the early 1970s.
Hepatitis A and E are mainly spread by contaminated food and water. [3] Hepatitis B is mainly sexually transmitted, but may also be passed from mother to baby during pregnancy or childbirth and spread through infected blood. [3] Hepatitis C is commonly spread through infected blood such as may occur during needle sharing by intravenous drug ...
Baruch Samuel Blumberg (July 28, 1925 – April 5, 2011), known as Barry Blumberg, was an American physician, geneticist, and co-recipient of the 1976 Nobel Prize in Physiology or Medicine (with Daniel Carleton Gajdusek), for his work on the hepatitis B virus while an investigator at the NIH and at the Fox Chase Cancer Center. [3]