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Synthetic virology is a branch of virology engaged in the study and engineering of synthetic man-made viruses.It is a multidisciplinary research field at the intersection of virology, synthetic biology, computational biology, and DNA nanotechnology, from which it borrows and integrates its concepts and methodologies.
A genetically modified virus is a virus that has been altered or generated using biotechnology methods, and remains capable of infection. Genetic modification involves the directed insertion , deletion , artificial synthesis or change of nucleotide bases in viral genomes.
Viruses may undergo two types of life cycles: the lytic cycle and the lysogenic cycle. In the lytic cycle, the virus introduces its genome into a host cell and initiates replication by hijacking the host's cellular machinery to make new copies of the virus. [12] In the lysogenic life cycle, the viral genome is incorporated into the host genome.
This is an accepted version of this page This is the latest accepted revision, reviewed on 28 January 2025. Computer program that modifies other programs to replicate itself and spread Hex dump of the Brain virus, generally regarded as the first computer virus for the IBM Personal Computer (IBM PC) and compatibles A computer virus is a type of malware that, when executed, replicates itself by ...
Pseudotyping allows one to control the expression of envelope proteins. A frequently used protein is the glycoprotein G (VSV-G) from the Vesicular stomatitis virus (VSV) which mediates entry via the LDL receptor. Envelope proteins incorporated into the pseudovirus allow the virus to readily enter different cell types with the corresponding host ...
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Baltimore classification groups viruses together based on their manner of mRNA synthesis. Characteristics directly related to this include whether the genome is made of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), the strandedness of the genome, which can be either single- or double-stranded, and the sense of a single-stranded genome, which is either positive or negative.
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