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Newborn hypoxic-ischaemic brain injury differs from injury in the adult brain in several ways: NMDA receptor toxicity is much higher in the immature brain. [18] Apoptotic mechanisms including activation of caspases, translocation of apoptosis-inducing factor and cytochrome-c release are much greater in the immature than the adult.
While common folklore says that people lose most of their heat through their heads, heat loss from the head is no more significant than that from other uncovered parts of the body. [ 52 ] [ 53 ] However, heat loss from the head is significant in infants, whose head is larger relative to the rest of the body than in adults.
In shivering, the heat is the main intended product and is utilized for warmth. [citation needed] Newborn babies, infants, and young children experience a greater (net) heat loss than adults because of greater surface-area-to-volume ratio. As they cannot shiver to maintain body heat, [citation needed] they rely on non-shivering thermogenesis.
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Manifestations: When the newborn cries, there is a reversal of blood flow through the foramen ovale which causes the newborn to appear mildly cyanotic in the first few days of life. The heart rate of the newborn should be between 110 and 160 beats per minute and it is common for the heart rate to be irregular in the first few hours following birth.
A 4-month-old infant died after she was exposed to extreme heat while visiting Lake Havasu in Arizona with her parents. The Mohave County Sheriff’s Office confirms to TODAY that Tanna Rae ...
A higher ratio of body surface area (proportional to heat loss) to body volume (proportional to heat production) A higher proportional surface area of the head; A low amount of musculature and the inability to shiver; A lack of thermal insulation, e.g., subcutaneous fat and fine body hair (especially in prematurely born children)
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