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  2. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  3. Pinealocyte - Wikipedia

    en.wikipedia.org/wiki/Pinealocyte

    Melatonin synthesis is also regulated by the nervous system. Nerve fibers in the retinohypothalamic tract connect the retina to the suprachiasmatic nucleus (SCN). The SCN stimulates the release of norepinephrine from sympathetic nerve fibers from the superior cervical ganglia that synapse with the pinealocytes.

  4. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin is a naturally occurring hormone produced in the brain that is also used as a dietary supplement and medication. [ 9 ] [ 12 ] As a hormone, melatonin is released by the pineal gland and is involved in sleep–wake cycles .

  5. 7 Ways to Improve Your "Sleep Hygiene" & Get a Good Night's Rest

    www.aol.com/7-ways-improve-sleep-hygiene...

    Melatonin. Melatonin is naturally produced in the brain. The hormone rises at bedtime, peaks in the middle of the night, and then decreases until it’s time to wake up. Supplemental melatonin may ...

  6. Pineal gland - Wikipedia

    en.wikipedia.org/wiki/Pineal_gland

    It produces melatonin, a serotonin-derived hormone, which modulates sleep patterns following the diurnal cycles. [2] The shape of the gland resembles a pine cone , which gives it its name. [ 3 ] The pineal gland is located in the epithalamus , near the center of the brain, between the two hemispheres , tucked in a groove where the two halves of ...

  7. Epithalamus - Wikipedia

    en.wikipedia.org/wiki/Epithalamus

    The secretion of melatonin happens in a cycle. Secretion is high at night or in the absence of light and low during the day. The suprachiasmatic nucleus in the hypothalamus is responsible for this cycle of secretion from the epithalamus, specifically from the pineal gland. [ 8 ]

  8. Expert tips to handle the winter blues - AOL

    www.aol.com/expert-tips-handle-winter-blues...

    Melatonin, a hormone produced in response to darkness, helps regulate the timing of your circadian rhythms and sleep. As darker winter days come around, some people may produce more melatonin.

  9. Chronobiotic - Wikipedia

    en.wikipedia.org/wiki/Chronobiotic

    Melatonin is a natural hormone produced by the body to encode nighttime. Endogenous melatonin is secreted daily in all mammals beginning after sunset and ending just before sunrise. Melatonin's chronobiotic property was initially suspected in the late 1980s when a high density of high-affinity melatonin receptors was discovered in the SCN ...