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[3] [4] In vitro studies have shown it to inhibit the enzymes that degrade cartilage and bone, as well as suppress inflammation and stimulate the synthesis of replacement cartilage. While it can cause an increased risk of bleeding, it is relatively safe and has a high LD50. PSGAG is one of the most widely prescribed joint treatments for horses. [5]
Imiquimod has also been tested for treatment of vulvar intraepithelial neoplasia, [30] vaginal intraepithelial neoplasia, [31] common warts (a 2012 Cochrane review found no randomized controlled trials), [32] plantar warts, [33] warts in people with suppressed immune systems, [34] flat warts on face and neck, [33] and warts under and around ...
HA, a linear polysaccharide, is composed of repeating disaccharide units of →4)GlcAβ(1→3)GlcNAcβ(1→ and has a very high molecular mass, ranging from 10 5 to 10 7 Da. Each HAS enzyme is capable of transglycosylation when supplied with UDP-GlcA and UDP-GlcNAc.
Consuming foods that contribute to the skin's health, such as zinc-rich foods, protein-rich foods, and foods high in vitamin A, C, and D, can help suppress stretch marks. [19] A systematic review has not found evidence that creams and oils are useful for preventing or reducing stretch marks in pregnancy. [ 3 ]
It is also used for the treatment of multidrug-resistant tuberculosis. [10] It is used by injection into a vein using an IV or into a muscle. [9] Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. [9] Other side effects include paralysis, resulting in the inability to breathe. [9]
Alfred Blaschko, a private practice dermatologist from Berlin, first described and drew the patterns of the lines of Blaschko in 1901. He obtained his data by studying over 140 patients with various nevoid and acquired skin diseases and transposed the visible patterns the diseases followed onto dolls and statues, then compiled the patterns onto a composite schematic of the human body.
The lines were first discovered in 1861 by Austrian anatomist Karl Langer (1819–1887), [1] [2] [3] though he cited the surgeon Baron Dupuytren as being the first to recognise the phenomenon. Langer punctured numerous holes at short distances from each other into the skin of a cadaver with a tool that had a circular-shaped tip, similar to an ...
The horizontal mattress stitch is a suture technique used to close wounds.It everts skin well and spreads tension along the wound edge. [1] [2] [3] This makes it ideal for holding together fragile skin [4] as well as skin under high tension such as the distant edges of a large laceration or as the initial holding suture in complicated repairs.