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Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.
E-SCREEN is a cell proliferation assay based on the enhanced proliferation of human breast cancer cells in the presence of estrogen active substances. The E-SCREEN test is a tool to easily and rapidly assess estrogenic activity of suspected xenoestrogens (singly or in combination).
ER is an American medical drama television series created by Michael Crichton that aired on NBC from September 19, 1994, to April 2, 2009, with a total of 331 episodes spanning 15 seasons. It was produced by Constant c Productions and Amblin Television , in association with Warner Bros. Television .
Diagnostic odds ratios less than one indicate that the test can be improved by simply inverting the outcome of the test – the test is in the wrong direction, while a diagnostic odds ratio of exactly one means that the test is equally likely to predict a positive outcome whatever the true condition – the test gives no information.
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
17345 Ensembl ENSG00000148773 ENSMUSG00000031004 UniProt P46013 E9PVX6 RefSeq (mRNA) NM_001145966 NM_002417 NM_001081117 RefSeq (protein) NP_001139438 NP_002408 NP_001074586 Location (UCSC) Chr 10: 128.1 – 128.13 Mb Chr 7: 135.29 – 135.32 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Antigen Kiel 67, also known as Ki-67 or MKI67 (marker of proliferation Kiel 67), is a protein ...
Here "T+" or "T−" denote that the result of the test is positive or negative, respectively. Likewise, "D+" or "D−" denote that the disease is present or absent, respectively. So "true positives" are those that test positive (T+) and have the disease (D+), and "false positives" are those that test positive (T+) but do not have the disease (D ...
In statistics, the 68–95–99.7 rule, also known as the empirical rule, and sometimes abbreviated 3sr, is a shorthand used to remember the percentage of values that lie within an interval estimate in a normal distribution: approximately 68%, 95%, and 99.7% of the values lie within one, two, and three standard deviations of the mean, respectively.