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The specific complications or events most linked to schizophrenia, and the mechanisms of their effects, are still under examination. [ 46 ] There is some evidence that exposure to toxins such as lead can also increase the risk of schizophrenia spectrum disorders.
People with schizophrenia are at a higher than average risk of physical ill health, and earlier death than the general population. [1] [2] [3] The fatal conditions include cardiovascular, respiratory and metabolic disorders. [4]
Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations ... (e.g. complications from an increased rate of cigarette smoking), or ...
Cannabis is a known risk factor for developing psychosis that can progress to schizophrenia but this is the first time researchers have found brain-level changes in an at-risk population in real time.
Complications: Self-harm, suicide [2] Causes: Mental illness (schizophrenia, bipolar disorder), trauma, sleep deprivation, some medical conditions, certain medications, drugs (including alcohol, caffeine and cannabis) [1] Treatment: Antipsychotics, counselling, social support [2] Prognosis: Depends on cause [2] Frequency
Rates of drug use amongst people with schizophrenia are higher than the general population; 50% of those diagnosed with schizophrenia use substances over their life. [6]: 495, 496 There is a model that suggests this arises because those with schizophrenia self-medicate with psychoactive drugs. [6]: 500
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