Search results
Results From The WOW.Com Content Network
In this case, the basic level of DNA compaction is the nucleosome, where the double helix is wrapped around the histone octamer containing two copies of each histone H2A, H2B, H3 and H4. Linker histone H1 binds the DNA between nucleosomes and facilitates packaging of the 10 nm "beads on the string" nucleosomal chain into a more condensed 30 nm ...
The structure of the condensed chromatin is thought to be loops of 30 nm fibre to a central scaffold of proteins. It is, however, not well-characterised. Chromosome scaffolds play an important role to hold the chromatin into compact chromosomes. Loops of 30 nm structure further condense with scaffold, into higher order structures. [19]
The DNA is thus condensed about ten-thousand-fold. [33] The chromosome scaffold, which is made of proteins such as condensin, TOP2A and KIF4, [34] plays an important role in holding the chromatin into compact chromosomes. Loops of thirty-nanometer structure further condense with scaffold into higher order structures. [35]
Chromomeres are organized in a discontinuous linear pattern along the condensed chromosomes (pachytene chromosomes) during the prophase stage of meiosis. [2] The linear pattern of chromomeres is linked to the arrangement of genes along the chromosome. [2] [3] Chromomeres contain genes and sometimes clusters of genes within their structure. [3]
DNA that was replicated in interphase is condensed from DNA strands with lengths reaching 0.7 μm down to 0.2-0.3 μm. [3] This process employs the condensin complex. [11] Condensed chromosomes consist of two sister chromatids joined at the centromere. [12]
Eukaryotic chromosomes are also stored in the cell nucleus, while chromosomes of prokaryotic cells are not stored in a nucleus. Eukaryotic chromosomes require a higher level of packaging to condense the DNA molecules into the cell nucleus because of the larger amount of DNA.
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
MatP condenses DNA in the Ter domain because the lack of MatP increased the distance between two fluorescent DNA markers located 100-kb apart in the Ter domain. Furthermore, MatP is a critical player in insulating the Ter domain from the rest of the chromosome. [126]