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  2. Octreotide - Wikipedia

    en.wikipedia.org/wiki/Octreotide

    Octreotide is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), when surgery is contraindicated, pituitary tumors that secrete thyroid-stimulating hormone (thyrotropinoma), [citation needed] diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors ().

  3. Octreotide scan - Wikipedia

    en.wikipedia.org/wiki/Octreotide_scan

    An octreotide scan is a type of SPECT scintigraphy used to find carcinoid, pancreatic neuroendocrine tumors, and to localize sarcoidosis. It is also called somatostatin receptor scintigraphy (SRS). Octreotide , a drug similar to somatostatin , is radiolabeled with indium-111 , [ 1 ] and is injected into a vein and travels through the bloodstream.

  4. DOTA-TATE - Wikipedia

    en.wikipedia.org/wiki/DOTA-TATE

    68 Ga DOTA-TATE (gallium-68 dotatate, GaTate) is used to measure tumor SSR density and whole-body bio-distribution via PET imaging. [11] [12] 68 Ga DOTA-TATE imagery has a much higher sensitivity and resolution compared to 111 In octreotide gamma camera or SPECT scans, due to intrinsic modality differences. [11]

  5. Octreotate - Wikipedia

    en.wikipedia.org/wiki/Octreotate

    Octreotate or octreotide acid is a somatostatin analogue that is closely related to octreotide. Its amino acid sequence is H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-OH

  6. Neuroendocrine tumor - Wikipedia

    en.wikipedia.org/wiki/Neuroendocrine_tumor

    Octreotide is a synthetic modification of somatostatin with a longer half-life. [ citation needed ] OctreoScan, also called somatostatin receptor scintigraphy (SRS or SSRS), utilizes intravenously administered octreotide that is chemically bound to a radioactive substance, often indium -111, to detect larger lesions with tumor cells that are ...

  7. Somatostatin receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Somatostatin_receptor...

    Some agonists were already approved by the FDA for clinical use, such as In-DTPA-octreotide and Ga-DOTATATE. [4] Development started after the discovery of modifications that can be done to the octreotide group, a ssrt selective subtype agonist, to cause its agonistic effects to be lost and gain antagonistic effects. [8]

  8. Somatostatin - Wikipedia

    en.wikipedia.org/wiki/Somatostatin

    Octreotide (brand name Sandostatin, Novartis Pharmaceuticals) is an octapeptide that mimics natural somatostatin pharmacologically, though is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone, and has a much longer half-life (about 90 minutes, compared to 2–3 minutes for somatostatin). Since it is ...

  9. Congenital hyperinsulinism - Wikipedia

    en.wikipedia.org/wiki/Congenital_hyperinsulinism

    Octreotide is administrated as a subcutaneous injection typically every 6 hours but it can also be administrated continuously through a subcutaneous pump. Long-acting somatostatin analogues, octreotide LAR (administrated intramuscularly) and lanreotide (administered as a deep subcutaneous injection), are a convenient option for older children.