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Selenium is toxic in high concentrations. As sodium selenite, the chronic toxic dose for human beings was described as about 2.4 to 3 milligrams of selenium per day. [7] In 2000, the US Institute of Medicine set the adult Tolerable upper intake levels (UL) for selenium from all sources - food, drinking water and dietary supplements - at 400 μg/day. [8]
Selenium deficiency occurs when an organism lacks the required levels of selenium, a critical nutrient in many species.Deficiency, although relatively rare in healthy well-nourished individuals, [1] can have significant negative results, [2] affecting the health of the heart and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation.
Selenomethionine is readily available as a dietary supplement. It has been suggested by nutritionists that selenomethionine, as an organic form of selenium, is easier for the human body to absorb than selenite, which is an inorganic form. [8] It was determined in a clinical trial that selenomethionine is absorbed 19% better than selenite. [8]
Sodium selenate is produced by oxidation of selenium, first with nitric acid, producing selenous acid.The selenous acid is neutralized to form sodium selenite.The sodium selenite is oxidized in a basic medium hydrogen peroxide to form a selenate, which is then spray-dried.
Selenite, satin spar, desert rose, and gypsum flower are crystal habit varieties of the mineral gypsum.. All varieties of gypsum, including selenite and alabaster, are composed of calcium sulfate dihydrate (meaning that it has two molecules of water), with the chemical formula CaSO 4 ·2H 2 O. Selenite contains no selenium, the similar names both derive from Greek selḗnē (σελήνη 'Moon').
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Large amounts of selenium are toxic; however, it is physiologically necessary for animals in extremely small amounts.Many other uncharacterized selenium-containing organic chemicals are also produced by a method similar to that of selenomethionine; some have recently been characterized but remain relatively unknown, such as S-seleno-methyl-glutathione and glutathione-S-selenoglutathione.