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Wolff's law, developed by the German anatomist and surgeon Julius Wolff (1836–1902) in the 19th century, states that bone in a healthy animal will adapt to the loads under which it is placed. [1] If loading on a particular bone increases, the bone will remodel itself over time to become stronger to resist that sort of loading.
The basis of osteogenic loading stems from Wolff's law, [5] which shows that the force or loading on bone through its axis, can stimulate the bone's natural function of increasing in density. Further study has shown that greater loads on bone can stimulate a greater effect of the body to respond and increase the density of bone, and can show ...
The cortical bone gives bone its smooth, white, and solid appearance, and accounts for 80% of the total bone mass of an adult human skeleton. [10] ... (Wolff's law).
Wolff's law: Bone adapts to pressure, or a lack of it. [19] Woodward–Hoffmann rules, in organic chemistry, predict the stereochemistry of pericyclic reactions based on orbital symmetry. Wright's law also known as Experience curve effects postulates that as production doubles, the cost of production will decline by a constant percentage.
Stress shielding is the reduction in bone density as a result of removal of typical stress from the bone by an implant (for instance, the femoral component of a hip prosthesis). [1] This is because by Wolff's law, [2] bone in a healthy person or animal remodels in response to the loads it is placed under. It is possible to mention the elastic ...
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
the histological proof of micro-damages in human bone biopsies; the basic model of the adaptation of the Growth plate to mechanical stress; the Utah-Paradigm of Bone physiology (Mechanostat-Theorem), an enhancement of Wolff's law stating that Bone adapts to mechanical stress and that hence there is a close link between muscle and bone
Hence, bone adapts its mechanical properties according to the needed mechanical function: bone mass, bone geometry, and bone strength (see also Stress-strain index, SSI) adapt to everyday usage/needs. "Maximal force" in this context is a simplification of the real input to bone that initiates adaptive changes.