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Wolff's law, developed by the German anatomist and surgeon Julius Wolff (1836–1902) in the 19th century, states that bone in a healthy animal will adapt to the loads under which it is placed. [1] If loading on a particular bone increases, the bone will remodel itself over time to become stronger to resist that sort of loading.
Cancellous bone or spongy bone, [12] [11] also known as trabecular bone, is the internal tissue of the skeletal bone and is an open cell porous network that follows the material properties of biofoams. [13] [14] Cancellous bone has a higher surface-area-to-volume ratio than cortical bone and it is less dense. This makes it weaker and more flexible.
The basis of osteogenic loading stems from Wolff's law, [5] which shows that the force or loading on bone through its axis, can stimulate the bone's natural function of increasing in density. Further study has shown that greater loads on bone can stimulate a greater effect of the body to respond and increase the density of bone, and can show ...
The Mechanostat is often defined as a practical description of Wolff's law described by Julius Wolff (1836–1902), but this is not completely accurate. Wolff wrote his treatises on bone after images of bone sections were described by Culmann and von Meyer, who suggested that the arrangement of the struts (trabeculae) at the ends of the bones ...
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
Proposed 25% U.S. tariffs on Canada and Mexico could lead to a sharp increase in vehicle prices, auto industry executives and analysts say.
Stress shielding is the reduction in bone density as a result of removal of typical stress from the bone by an implant (for instance, the femoral component of a hip prosthesis). [1] This is because by Wolff's law, [2] bone in a healthy person or animal remodels in response to the loads it is placed under. It is possible to mention the elastic ...
The Colorado Rockies added another piece to their bullpen on Wednesday by agreeing to a $2 million, one-year deal with left-hander Scott Alexander. The 35-year-old Alexander is coming off a season ...