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Azelastine, sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. [5] [6] Other uses may include asthma and skin rashes for which it is taken by mouth. [7]
European Union, Canada, Australia Hepatotoxicity [3] Tolrestat (Alredase) 1996 Argentina, Canada, Italy, others Severe hepatotoxicity [3] Triacetyldiphenolisatin: 1971 Australia Hepatotoxicity. [3] Triazolam: 1991 France, Netherlands, Finland, Argentina, UK others Psychiatric adverse drug reactions, amnesia. [3] [66] Triparanol: 1962 France, US
Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [1] [2] When initiated by the clinician, it is known as deprescribing. [3]
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Founded in 1974 by Barry Sherman, the company is the largest producer of generic drugs in Canada, with annual sales exceeding CA$2.5 billion. [5] By 2023, Apotex employed close to 8,000 people as Canada's largest drug manufacturer, with over 300 products selling in over 115 countries.
Actavis Generics [1] (formerly known as Watson Pharmaceuticals and Actavis plc, prior to the acquisition of Irish-based Allergan, Inc.) is a global pharmaceutical company focused on acquiring, developing, manufacturing and marketing branded pharmaceuticals, generic and over-the-counter medicines, and biologic products.
Excedrin is no longer sold in Canada. [11] Previously, Excedrin Migraine and Excedrin Extra Strength sold in Canada had a different formulation compared to the United States. In Canada the product sold with those names contained 500 mg of acetaminophen and 65 mg of caffeine per tablet.
Ronzoni pastina has been discontinued, but the pasta brand says it "hasn't given up" on bringing the star-shaped pasta back. (Photo: Ronzoni via Instagram/Getty Images)
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