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Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
This problem, called the cosmological constant problem, is a hierarchy problem very similar to that of the Higgs boson mass problem, since the cosmological constant is also very sensitive to quantum corrections, but it is complicated by the necessary involvement of general relativity in the problem.
Smale's problems is a list of eighteen unsolved problems in mathematics proposed by Steve Smale in 1998 [1] and republished in 1999. [2] Smale composed this list in reply to a request from Vladimir Arnold, then vice-president of the International Mathematical Union, who asked several mathematicians to propose a list of problems for the 21st century.
A problem set, sometimes shortened as pset, [1] is a teaching tool used by many universities. Most courses in physics, math, engineering, chemistry, and computer science will give problem sets on a regular basis. [2] They can also appear in other subjects, such as economics.
Problems 1, 2, 5, 6, [g] 9, 11, 12, 15, 21, and 22 have solutions that have partial acceptance, but there exists some controversy as to whether they resolve the problems. That leaves 8 (the Riemann hypothesis), 13 and 16 [h] unresolved, and 4 and 23 as too vague to ever be described as solved. The withdrawn 24 would also be in this class.
In crystallography, direct methods are a family of methods for estimating the phases of the Fourier transform of the scattering density from the corresponding magnitudes. . The methods generally exploit constraints or statistical correlations between the phases of different Fourier components that result from the fact that the scattering density must be a positive real nu
Mathematical chemistry [1] is the area of research engaged in novel applications of mathematics to chemistry; it concerns itself principally with the mathematical modeling of chemical phenomena. [2] Mathematical chemistry has also sometimes been called computer chemistry , but should not be confused with computational chemistry .
An artificially produced word problem is a genre of exercise intended to keep mathematics relevant. Stephen Leacock described this type: [ 1 ] The student of arithmetic who has mastered the first four rules of his art and successfully striven with sums and fractions finds himself confronted by an unbroken expanse of questions known as problems.