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  2. Forward genetics - Wikipedia

    en.wikipedia.org/wiki/Forward_genetics

    Forward genetics can be thought of as a counter to reverse genetics, which determines the function of a gene by analyzing the phenotypic effects of altered DNA sequences. [2] Mutant phenotypes are often observed long before having any idea which gene is responsible, which can lead to genes being named after their mutant phenotype (e.g ...

  3. Genetic linkage - Wikipedia

    en.wikipedia.org/wiki/Genetic_linkage

    Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.

  4. Genetic hitchhiking - Wikipedia

    en.wikipedia.org/wiki/Genetic_hitchhiking

    The increase in variance between replicate populations due to drift is independent, whereas with draft it is autocorrelated, i.e. if an allele frequency goes up because of genetic drift, that contains no information about the next generation, whereas if it goes up because of genetic draft, it is more likely to go up than down in the next ...

  5. Genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering

    Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology.It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms.

  6. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    The transferred DNA is piloted to the plant cell nucleus and integrated into the host plants genomic DNA.The plasmid T-DNA is integrated semi-randomly into the genome of the host cell. [ 29 ] By modifying the plasmid to express the gene of interest, researchers can insert their chosen gene stably into the plants genome.

  7. Chromosomal crossover - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_crossover

    The first theory rests upon the idea that meiosis evolved as another method of DNA repair, and thus crossing-over is a novel way to replace possibly damaged sections of DNA. [9] The second theory comes from the idea that meiosis evolved from bacterial transformation , with the function of propagating diversity.

  8. DNA transposon - Wikipedia

    en.wikipedia.org/wiki/DNA_transposon

    DNA transposons are DNA sequences, sometimes referred to "jumping genes", that can move and integrate to different locations within the genome. [1] They are class II transposable elements (TEs) that move through a DNA intermediate, as opposed to class I TEs, retrotransposons , that move through an RNA intermediate. [ 2 ]

  9. Chromosomal translocation - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_translocation

    A type of DNA repair that has a major role in generating chromosomal translocations is the non-homologous end joining pathway. [ 16 ] [ 17 ] When this pathway functions appropriately it restores a DNA double-strand break by reconnecting the originally broken ends, but when it acts inappropriately it may join ends incorrectly resulting in ...