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Maternal physiological changes in pregnancy are the adaptations that take place during pregnancy that enable the accommodation of the developing embryo and fetus. These are normal physiological adaptations that cause changes in behavior , the functioning of the heart , blood vessels , and blood , metabolism including increases in blood sugar ...
High levels of prolactin during pregnancy and breastfeeding also increase insulin resistance, increase growth factor levels (IGF-1) and modify lipid metabolism in preparation for breastfeeding. During lactation, prolactin is the main factor maintaining tight junctions of the ductal epithelium and regulating milk production through osmotic balance.
The breasts change during pregnancy to prepare for lactation, and more changes occur immediately after the birth. Progesterone is the hormone that influences the growth of breast tissue before the birth. Afterwards, the endocrine system shifts from producing hormones that prevent lactation to ones that trigger milk production. [3]
While breastfeeding, prolactin suppresses gonadotropin secretion, potentially delaying ovulation. Ovulation may resume before the return of menstruation during this time. [2] Although hyperprolactinemia can result from normal physiological changes during pregnancy and breastfeeding, it can also be caused by other etiologies.
Mother with newborn baby. The postpartum (or postnatal) period begins after childbirth and is typically considered to last for six weeks. [1] There are three distinct phases of the postnatal period; the acute phase, lasting for six to twelve hours after birth; the subacute phase, lasting six weeks; and the delayed phase, lasting up to six months.
In women, hyperprolactinemia is often associated with amenorrhea, a condition that resembles the physiological situation during lactation (lactational amenorrhea). Mechanical detection of suckling increases prolactin levels in the body to increase milk synthesis.
The embryo upregulates hCG, drives growth of the cell, and upregulates P4 production driving development. hCG and P4 direct changes in the mother to enable successful pregnancy (see below) via upregulation of specific hormones that act to direct both endocrinological and biological changes within the mother for successful pregnancy.
The estrous cycle (from Latin oestrus 'frenzy', originally from Ancient Greek οἶστρος (oîstros) 'gadfly') is a set of recurring physiological changes induced by reproductive hormones in females of mammalian subclass Theria. [1]