Search results
Results From The WOW.Com Content Network
Binswanger's disease, also known as subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy, [1] is a form of small-vessel vascular dementia caused by damage to the white brain matter. [2] White matter atrophy can be caused by many circumstances including chronic hypertension as well as old age. [3]
In subcortical dementia, there is targeted damage to regions lying under the cortex. The pathological process that result in subcortical dementia shows neuronal changes that involve primarily the thalamus , basal ganglia , and rostral brain-stem nuclei and mostly, some projections in the white matter from these regions to the cortex, with ...
White softening is another form of cerebral softening. This type of softening occurs in areas that continue to be poorly perfused, with little to no blood flow. These are known as "pale" or "anemic infarcts" and are areas that contain dead neuronal tissue , which result in a softening of the cerebrum.
Subtypes of vascular dementia include subcortical vascular dementia, multi-infarct dementia, stroke-related dementia, and mixed dementia. [2] [5] Subcortical vascular dementia occurs from damage to small blood vessels in the brain. Multi-infarct dementia results from a series of small strokes affecting several brain regions.
CADASIL or CADASIL syndrome, involving cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, is the most common form of hereditary stroke disorder and is thought to be caused by mutations of the NOTCH3 gene on chromosome 19. [1]
Patients often exhibit diffuse swelling of the cerebral white matter and large subcortical cysts in the frontal and temporal lobes, with cysts developing on the tips of the temporal and subcortical areas. Other significant central nervous system symptoms include diffuse spongiform leukoencephalopathy and vacuolizing myelinopathy. In vacuolizing ...
Symptoms: Same symptoms as ischemic stroke, but unconsciousness, headache, nausea, stiff neck, and seizures are more often in brain hemorrhages than ischemic strokes: Complications: Coma, persistent vegetative state, cardiac arrest (when bleeding is in the brain stem or is severe), death: Types
Common symptoms in infants include lack of motor skills, weak muscle tone, and macrocephaly. [4] It may also be accompanied by difficulties in feeding and swallowing, seizures and sleep disturbances. [4] Affected children typically die before the age of 10, but life expectancy can vary. [5]