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Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria , with greater activity against both types of organism than third-generation agents.
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Cefepime/enmetazobactam, sold under the brand name Exblifep, is a medication used for the treatment of urinary tract infections. [ 1 ] [ 2 ] It is a fixed dose combination containing cefepime , a cephalosporin antibacterial; and enmetazobactam , a beta-lactamase inhibitor .
Cefepime: Maxipime: H: P Gram-positive: They are extended-spectrum agents with similar activity against Gram-positive organisms as first-generation cephalosporins. [citation needed] Gram-negative: Fourth-generation cephalosporins are zwitterions that can penetrate the outer membrane of Gram-negative bacteria. [32]
Here are links to possibly useful sources of information about Cefepime. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
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Cefepime: Maxipime: Covers pseudomonal infections. Gastrointestinal upset and diarrhea; Nausea (if alcohol taken concurrently) Allergic reactions; Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Cephalosporins (Fifth generation) Ceftaroline fosamil: Teflaro: Used to ...
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