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It is published by Elsevier on behalf of the International Society for Heart and Lung Transplantation, of which is the official journal. The editor-in-chief is Mandeep R. Mehra (Harvard Medical School). According to the Journal Citation Reports, the journal has a 2021 impact factor of 13.569, the highest of any journal in cardiothoracic surgery ...
The International Society for Heart and Lung Transplantation (ISHLT), established in 1981, [2] is a professional organization committed to research and education in heart and lung disease and transplantation. [1] It holds annual scientific meetings and publishes The Journal of Heart and Lung Transplantation. [2]
A heart–lung transplant is a procedure carried out to replace both failing heart and lungs in a single operation. Due to a shortage of suitable donors and because both heart and lung have to be transplanted together, it is a rare procedure; only about a hundred such transplants are performed each year in the United States.
Ex vivo lung perfusion, EVLP, is a form of machine perfusion aimed at sustaining the active aerobic cellular metabolism of donor lungs outside the donor's body prior to lung transplantation. This medical preservation technique typically occurs within a specialised machine engineered to mimic the conditions of the natural circulatory system .
Machine perfusion (MP) is an artificial perfusion technique often used for organ preservation to help facilitate organ transplantation.MP works by continuously pumping a specialized solution through donor organs, mimicking the body's natural blood flow while actively controlling temperature, oxygen levels, chemical composition, and mechanical stress within the organ.
A beating heart awaiting transplant. American medical researcher Simon Flexner was one of the first people to mention the possibility of heart transplantation. In 1907, he wrote the paper "Tendencies in Pathology," in which he said that it would be possible one day by surgery to replace diseased human organs – including arteries, stomach, kidneys and heart.
A thoracotomy is a surgical procedure to gain access into the pleural space of the chest. [1] It is performed by surgeons (emergency physicians or paramedics under certain circumstances) to gain access to the thoracic organs, most commonly the heart, the lungs, or the esophagus, or for access to the thoracic aorta or the anterior spine (the latter may be necessary to access tumors in the spine).
Lung transplantation is the therapeutic measure of last resort for patients with end-stage lung disease who have exhausted all other available treatments without improvement. A variety of conditions may make such surgery necessary. As of 2005, the most common reasons for lung transplantation in the United States were: [2]